TABLE 3.
Acquired carriage of high-level AmpC cephalosporinase-producing Enterobacteriaceae during the intensive care unit stay in patients not colonized at admission: results of logistic regression analysesa
| Variable | Bivariate logistic regression, unadjusted OR (95% CI) | Multivariate logistic regression, adjusted OR (95% CI) |
|---|---|---|
| Type of ICU stay, surgical vs medical | 1.90 (1.06–3.40) | |
| SAPS II at ICU admission, per point increase | 1.02 (1.01–1.03) | 1.02 (1.01–1.04) |
| Main diagnoses of the ICU stay | ||
| Sepsis | 1.35 (0.87–2.10) | |
| Renal | 1.60 (1.03–2.29) | |
| Antimicrobial exposure during the ICU stay | ||
| Third- and fourth-generations cephalosporins, per day | 1.03 (1.00–1.07) | |
| Metronidazole, per day | 1.02 (1.01–1.03) | 1.09 (1.01–1.17) |
| Use of life-sustaining therapy during the ICU stay | ||
| Mechanical ventilation | 1.08 (1.02–1.13) | 1.62 (0.99–2.14) |
| Vasopressors | 1.77 (1.14–2.76) | |
| Renal replacement therapy | 2.04 (1.19–3.50) | |
| Length of ICU stay, per day | 1.02 (1.01–1.03) | 1.03 (1.01–1.04) |
a
OR, odds ratio; 65% CI, 95% confidence interval; ICU, intensive care unit; SAPS II, simplified acute physiology score II.