Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Prospective validation study from the predictions of a mathematical model regarding total cell kill and resistant subpopulation amplification. (a) An exposure calculated to expand the resistant subpopulation was employed (AUC/MIC ratio = 52). (b) An exposure that was calculated to suppress mutant subpopulation amplification was employed (AUC/MIC ratio = 157). The lines are prospective prediction lines and not best-fit lines.
