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Relationship of active-compound potencies between inhibition of Plasmodium liver and blood stages. The compounds are plotted against their P. berghei liver-stage and P. falciparum blood-stage potencies (pXC50 = −logXC50, where XC50 is in molar units and pXC50 is dimensionless; an XC50 value of 1 μM corresponds to a pXC50 value of 6). The calculated Spearman's correlation (RS) is 0.414, with a P value of <0.0001; n = 101.
