TABLE 2.
Characteristics of Enterobacteriaceae with NDM-7 from Calgary, Canada, from 2013 to 2014
| Characteristic | KpN01 | SmN01 | EcN01 | EclcN01 | EcN02 | KpN12 |
|---|---|---|---|---|---|---|
| Patient | 1 | 2 | 2 | 3 | 3 | 4 |
| Hospital | A | B | B | A | A | A |
| Specimen | Urine | Urine | Rectal swab | Blood | Rectal swab | Urine |
| Date of clinical presentation | June 2013 | November 2013 | November 2013 | October 2014 | October 2014 | December 2014 |
| Susceptibilities (MIC, μg/ml) | ||||||
| TZP | >64/4 | >64/4 | >64/4 | >64/4 | >64/4 | >64/4 |
| FOX | >16 | >16 | >16 | >16 | >16 | >16 |
| CRO | >32 | >32 | >32 | >32 | >32 | >32 |
| CAZ | >16 | >16 | >16 | >16 | >16 | >16 |
| FEP | >16 | >16 | >16 | >16 | >16 | >16 |
| ATM | >16 | ≤4 | >16 | >16 | >16 | >16 |
| MEM | >8 | >8 | >8 | >8 | >8 | >8 |
| ERT | >4 | >4 | >4 | >4 | >4 | >4 |
| AMK | ≤4 | ≤4 | 16 | ≤4 | ≤4 | ≤4 |
| GEN | ≤1 | ≤1 | ≤1 | ≤1 | ≤1 | ≤1 |
| TOB | ≤1 | ≤1 | >8 | ≤1 | ≤1 | ≤1 |
| CIP | 1 | ≤0.5 | >2 | >2 | ≤0.5 | ≤0.5 |
| SXT | >2/38 | ≤2/38 | >2/38 | >2/38 | ≤2/38 | ≤2/38 |
| TGC | ≤1 | 2 | ≤1 | 1 | 1 | ≤1 |
| CST | 0.19 | >256 | 0.125 | 0.09 | 0.125 | 0.125 |
| FOF | 16 | >256 | 1 | 32 | 1 | 16 |
| MHT | Positive | Positive | Positive | Positive | Positive | Positive |
| Mastdiscs | MBL positive | MBL positive | MBL positive | MBL positive | MBL positive | MBL positive |
| Carbapenemase | NDM-7 | NDM-7 | NDM-7 | NDM-7 | NDM-7 | NDM-7 |
| MLST | ST654 | ST44 | ST113 | ST91 | ST138 | |
| Plasmid size(s) (kb) | 190, 130, 50 | 50 | 175, 105, 80, 55, 50 | 170, 80, 50 | 135, 50 | 200, 50 |
| Transconjugant (plasmid size, kb) | KpN01T (50) | SmN01T (50) | EcN01T (50) | EclcNT01T (50) | EcN02T (50) | KpN12T (50) |
| ERT MIC, μg/ml | 16 | 10 | 16 | 8 | 16 | 16 |
| MER MIC, μg/ml | 8 | 6 | 4 | 4 | 8 | 4 |
| IPM MIC, μg/ml | >32 | >32 | >32 | >32 | >32 | >32 |
| FOS MIC, μg/ml | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 |
| Replicon typing | IncX | IncX | IncX | IncX | IncX | IncX |