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Superposition of ADC-7- and KPC-2-bound S02030 structures. The protein is represented in stick and the inhibitors in ball-and-stick representations; KPC-2 is shown with cyan carbon atoms, whereas theADC-7 carbon coordinates are shown in medium blue. The Cα atoms of residues 67 to 84, 132 to 134, 231 to 238, and 243 to 249 of KPC-2 were superimposed onto ADC-7 residues 61 to 78, 152 to 154, 309 to 316, and 319 to 325, respectively, with an RMSD of 0.98 Å.
