Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Ceftazidime and meropenem PBP3 IC50 in wild-type PAO1 and selected PBP3 mutants
| Strain | IC50 (mg/liter) ± SD for: |
|
|---|---|---|
| PBP3 CAZ | PBP3 MER | |
| PAO1 | 0.13 ± 0.08 | 0.028 ± 0.003 |
| PAOMS.1-MER (PBP3 A539T) | 0.23 ± 0.07 | 0.089 ± 0.04a |
| PAOMS.3-MER (PBP3 F533L) | 0.18 ± 0.05 | 0.074 ± 0.04a |
P < 0.05 compared to wild-type PAO1.
