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. 2016 Feb 26;60(3):1560–1572. doi: 10.1128/AAC.02625-15

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FIG 3 — Ex vivo treatment of CD4⁺ T cells from cART-suppressed study animals with romidepsin. (A) Changes in acetylated histone H3 and H4 levels in CD4⁺ T cells from three study animals measured by flow cytometry 24 h after ex vivo treatment with DMSO or the indicated concentrations of RMD. (B) Quantification by qRT-PCR of virion-associated vRNA in culture supernatants of CD4⁺ T cells from 5 cART-suppressed study animals at the indicated time points posttreatment with DMSO or the indicated concentrations of RMD. P values for statistical comparisons between vehicle control (DMSO) treatment or the indicated concentrations of RMD are shown.