Table 1.
Participant characteristics.
| Total (%) |
Female (%) |
Male (%) |
Never smokers (%) |
Current smokers (%) |
Former smokers (%) | Age, mean (SD) | Age of onset, mean (SD) | CPD, mean (SD) |
|---|---|---|---|---|---|---|---|---|
| WHI SHARe | ||||||||
| Healthy | ||||||||
| N = 7097 (99.2%) | 7097 (100.0%) | – | 3,598 (50.7%) | 761 (10.7%) | 2,738 (38.6%) | 61.0 (6.8) | 20.9 (5.4) | 5.5 (8.5) |
| Lung cancer | ||||||||
| N = 59 (0.8%) | 59 (0.08%) | – | 14 (23.7%) | 18 (30.5%) | 27 (45.8%) | 63.6 (6.6) | 19.5 (4.1) | 14.4 (12.4) |
| UCSF, MD Anderson & Wayne State University Case–Control | ||||||||
| Healthy | ||||||||
| N = 822 (43.3%) | 404 (49.1%) | 418 (50.9%) | NA | 435 (52.9%) | 387 (47.1%) | 60.5 (10.2) | 16.9 (4.6) | 17.9 (13.9) |
| Lung cancer | ||||||||
| N = 1078 (56.7%) | 530 (49.2%) | 548 (50.8%) | NA | 660 (61.2%) | 418 (38.8%) | 63.0 (10.3) | 17.6 (4.9) | 20.2 (13.1) |
Legend: Abbreviations: WHI = Women's Health Initiative; SHARe = Single Nucleotide Polymorphism Health Association Resource; SD = standard deviation; % = percent healthy or lung cancer.
Note. The WHI study included only females. Never-smokers were not included in analyses of lung cancer outcomes.