Table 1.

Strategies used in the analyses of the structural proteome of herpesviruses.

Authors	Year of Publication	Virus	Separation Used	Targeted or Untargeted Identification	Mass Spec. Strategy
Davison et Davison [8]	1995	CCV	Gel based	Targeted	Peptide mass fingerprint
Nealon et al. [13]	2001	KSHV	Gel based	Targeted	LC MS/MS
Bortz et al. [14]	2003	MHV6	Gel based	Targeted	LC MS/MS
Varnum et al. [15]	2004	HCMV	Gel free (2D)	Untargeted	LC MS/MS
Johannsen et al. [16]	2004	EBV	Gel based	Untargeted	LC MS/MS
Kattenhorn et al. [17]	2004	MCMV	Gel based	Targeted	LC MS/MS
Bechtel et al. [18]	2005	KSHV	Gel based	Targeted	MS/MS (Maldi Tof/Tof)
Zhu et al. [19]	2005	KSHV	Gel based	Targeted	LC MS/MS
O’connor et al. [20]	2006	RRV	Gel free + Gel based	Untargeted	LC MS/MS
Michael et al. [21]	2006	PRV	Gel based (1D + 2D)	Targeted	Peptide mass fingerprint
Loret et al. [22]	2008	HSV-1	Gel based	Targeted	LC MS/MS
Dry et al. [23]	2008	AlHV1	Gel based	Untargeted	LC MS/MS
Kunec et al. [24]	2009	CCV	Gel free (2D)	Untargeted	LC MS/MS
Michel et al. [25]	2010	CyHV-3	Gel based + Gel free (2D)	Untargeted	LC MS/MS
Kramer et al. [26]	2011	PRV	Gel based + Gel free	Untargeted	Maldi + ESI MS/MS
Van Beurden et al. [27]	2011	AngHV-1	Gel based + Gel free (2D)	Untargeted	LC MS/MS
Lété et al. [28]	2012	BoHV-4	Gel based + Gel free (2D)	Untargeted	LC MS/MS
Vidick et al. [29]	2013	MuHV-4	Gel based	Untargeted	LC MS/MS

CCV: canine coronavirus; KSHV: Kaposi’s sarcoma-associated herpesvirus; MHV6: murine hepatitis virus; HCMV: human cytomegalovirus; EBV: Epstein–Barr virus; MCMV: mouse cytomegalovirus; RRV: Ross River virus; PRV: pseudorabies virus; HSV-1: herpes simplex virus type 1; AIHV1: Alcelaphine herpesvirus 1; CyHV-3: Cyprinid herpesvirus 3; AngHV-1: Anguillid herpesvirus 1; BoHV-4: Bovine herpesvirus 4; MuHV4: Murid herpesvirus 4.