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Elevated myelin oligodendrocyte glycoprotein (MOG)-specific immunoglobulin G (IgG) responses during acute infectious mononucleosis (IM). Serum anti-MOG IgG reactivity of control and IM patient sera from cohort 1 (A) and cohort 2 (B) was detected at time of diagnosis. The positivity threshold, designated with a grey dotted line, was determined by three standard deviations above the mean of the control samples; (C) MOG-specific IgG responses disappear six months post IM diagnosis.
