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. 2016 Mar 3;6:22348. doi: 10.1038/srep22348

Figure 1. Activation of Wg signaling induces cell death in Drosophila.

Figure 1

Light micrographs of Drosophila adult eyes and wings, and fluorescent micrographs of 3rd instar eye and wing discs are shown. Compared with the GMR-Gal4 control (a,a’), expression of Wg, Dsh or Arm induces cell death in eye discs indicated by AO staining (b’–d’) and produces adult eyes with reduced size (b–d). Compared with the ptc-Gal4 control (e,e’), expression of Dsh, Arm or Pan induces cell death in wing discs (f’–h’) and produces a loss-of-ACV phenotype in adult wings (f–h, the lower panels are high magnification of the boxed areas in upper panels). Scale bars: 100 μm in (a–d) and (e–h, upper panels); 50 μm in (a’–d’), (e–h, lower panels) and (e’–h’).