Table 1.
Clinical and biochemical characteristics
| Characteristics | Normotensive women | Prehypertensive women | Normotensive women with DM | Prehypertensive women with DM |
|---|---|---|---|---|
| (n = 20) | (n = 20) | (n = 20) | (n = 20) | |
| Age (years) | 42.7 ± 5.8 | 44.9 ± 4.0 | 45.2 ± 6.6 | 45.4 ± 5.1 |
| Height (cm) | 162.3 ± 5.7 | 160.5 ± 5.9 | 161.9 ± 6.1 | 161.1 ± 5.2 |
| Weight (Kg) | 58.7 ± 5.7 | 59.5 ± 5.7 | 62.1 ± 4.8 | 64.1 ± 4.4 |
| BMI (kg/cm2) | 23.5 ± 2.7 | 22.9 ± 2.1 | 24.0 ± 2.1 | 23.8 ± 1.5 |
| Systolic blood pressure (mmHg) | 108.8 ± 6.5 | 130.4 ± 5.5a | 111.0 ± 6.0 | 131.3 ± 4.9a |
| Diastolic blood pressure (mmHg) | 68.5 ± 5.0 | 80.3 ± 4.4a | 70.9 ± 4.8 | 80.9 ± 5.4a |
| Heart rate (beats/min) | 72.2 ± 7.9 | 72.8 ± 7.4 | 73.7 ± 10.2 | 75.0 ± 7.7 |
| AST (mmol/L) | 24.3 ± 5.8 | 26.9 ± 8.1 | 27.7 ± 6.0 | 25.7 ± 6.5 |
| ALT (mmol/L) | 22.9 ± 5.2 | 24.5 ± 5.1 | 24.8 ± 6.1 | 21.7 ± 5.7 |
| BUN (mmol/L) | 5.7 ± 0.8 | 5.5 ± 1.2 | 5.9 ± 1.3 | 5.4 ± 1.1 |
| Cr (mmol/L) | 72.2 ± 14.8 | 66.4 ± 16.4 | 73.1 ± 15.2 | 65.2 ± 18.0 |
| LDL (mmol/L) | 2.98 ± 0.33 | 2.88 ± 0.55 | 3.10 ± 0.37 | 3.09 ± 0.36 |
| TC (mmol/L) | 4.93 ± 0.44 | 4.92 ± 0.65 | 5.11 ± 0.39 | 5.08 ± 0.42 |
| HDL (mmol/L) | 1.37 ± 0.24 | 1.40 ± 0.21 | 1.31 ± 0.19 | 1.34 ± 0.16 |
| TG (mmol/L) | 1.44 ± 0.19 | 1.39 ± 0.17 | 1.50 ± 0.21 | 1.46 ± 0.12 |
| FPG (mmol/L) | 4.71 ± 0.67 | 4.51 ± 0.61 | 8.91 ± 1.16b | 8.73 ± 1.08b |
| 2hPG(mmol/L) | 6.25 ± 0.66 | 6.17 ± 0.67 | 10.87 ± 1.72b | 10.31 ± 1.61b |
| HbA1C(%) | 5.31 ± 0.58 | 5.18 ± 0.63 | 8.49 ± 1.47b | 8.15 ± 1.52b |
| hrCRP (mmol/L) | 0.961 ± 0.509 | 1.130 ± 0.615 | 1.953 ± 0.852b | 1.828 ± 0.882b |
| FMD(%) | 10.29 ± 1.16 | 9.79 ± 1.22 | 5.87 ± 5.49b | 5.49 ± 0.129b |
| GMD(%) | 22.49 ± 2.12 | 21.89 ± 2.45 | 21.05 ± 2.47 | 21.37 ± 2.68 |
Abbreviation: BMI body mass index, LDL low-density lipoprotein, TC total cholesterol, HDL high density lipoprotein, TG triglyeride, FPG fasting plasma glucose, 2hPG 2-h plasma glucose, HbA 1 C glycosylated hemoglobin, hrCRP hyper-sensitive C-reactive protein, GMD glyceryl trinitrate-mediated dilation, FMD flow-mediated brachial artery dilatation
Notes: Data are given as mean ± SD. avs normotension; bvs without DM