Table 1.
Intervention time/h | IC50 (uM) | Resistance index (RI) | |||||
---|---|---|---|---|---|---|---|
MCF-7 | MCF-7/ADR | MCF-7/ADR | |||||
CON | Lv-shNC | Lv-shSALL4 | CON | Lv-shNC | Lv-shSALL4 | ||
24 | 1.06 ± 0.09 | 152.57 ± 2.33 | 149.03 ± 3.28 | 42.09 ± 3.42** | 143.93 ± 2.20 | 140.60 ± 3.60 | 39.70 ± 33.23** |
48 | 0.22 ± 0.01 | 29.66 ± 1.14 | 30.01 ± 1.88 | 6.48 ± 0.42** | 134.82 ± 5.17 | 136.41 ± 5.40 | 29.63 ± 1.59** |
Lv-shSALL4 group vs. CON group
** P < 0.01