Table 1.
Imaging parameters of selected reports on ex vivo MRI of the embryonic and neonatal mouse brain.
Study | Age | Instrument | Contrast agent (Concentration) | Resolution | Contrast and Sequence | Scan time |
---|---|---|---|---|---|---|
Petiet et al., 2008 | E10.5–E19.5 P0–P32 | 9.4 T and 7 T | Prohance (20 mM) | 0.0195 × 0.0195 × 0.0195 mm | T1, 3D SE TE/TR = 5.2/75 ms | 3–12 h |
Aggarwal et al., 2015 | E12.5–E18.5 | 11.7 T | Magnevist (3 mM) | 0.052 × 0.052 × 0.052 mm | 3D dw- GRASE, b = 1400 s/mm2, 18 directions | 21.5–32 h |
Norris et al., 2015 | E15.5 | 9.4 T | Magnevist (2 mM) | 0.075 × 0.075 × 0.075 mm | 3D dw- FSE/SE, b = 1498 s/mm2, 42 directions | 76 h for 3D SE 19 h for 3D FSE |
dw, diffusion-weighted; FSE, fast spin echo; GRASE, gradient and spin echo; SE, spin echo; T, Telsa; TE, echo time; TR, repetition time.