Table 2.
Imaging parameters of selected reports on in vivo MRI of the embryonic and neonatal mouse brain.
Study | Age | Instrument | Contrast agent (Concentration) | Resolution | Contrast and Sequence | Scan time |
---|---|---|---|---|---|---|
Szulc et al., 2015 | P1–P11 | 7 T | MnCl2 (50 mg/kg maternal i.p. injection, 24 h prior MRI) | 0.1 × 0.1 × 0.1 mm | T1, 3D GE TE/TR = 3.6/50 ms | ~ 2 h |
Deans et al., 2008 | E12.5–E18.5 | 7 T | MnCl2 (up to 80 mg/kg maternal i.p. injection, 24 h prior MRI) | 0.1 × 0.1 × 0.1 mm | T1, 3D GE TE/TR = 5/40 ms | 70–90 min |
Wu et al., 2015 | E17 | 11.7 T | Magnevist (0.4 mMol/Kg, maternal i.p. injection, 2 h prior MRI) | 0.16 × 0.16 × 0.16 mm | 3D dw-GRASE, b = 1000 s/mm2, 30 directions | ~ 2 h |
dw, diffusion-weighted; FSE, fast spin echo; GRASE, gradient and spin echo; SE, spin echo; T, Telsa; TE, echo time; TR, repetition time.