Table 2.
Eighteen subsequent malignancies occurred in PPBL patients
| Patients | Delay between PPBL and subsequent malignancy’s diagnosis | Type of malignancy | Follow-up |
|---|---|---|---|
| UPN36 | 38 months | DLBCL | 56 months |
| UPN47 | 20 months | SMZL | +65 months |
| UPN57 | 92 months | DLBCL | 99 months |
| UPN63 | Diagnosis of PPBL and lymphoma was concomitant | DLBCL | +13 months |
| UPN71 | 77 months | SMZL | +86 months |
| UPN83 | 120 months | DLBCL | +131 months |
| UPN1 | 264 months | MGUS | +348 months |
| UPN10 | 144 months | MGUS | +148 months |
| UPN157 | 44 months | MGUS | +47 months |
| UPN118 | Diagnosis of PPBL and MGUS was concomitant | MGUS | +36 months |
| UPN163 | Diagnosis of PPBL and MGUS was concomitant | MGUS | +57 months |
| UPN105 | Diagnosis of PPBL and MGUS was concomitant | MGUS | +42 months |
| UPN5 | 96 months | Mammary carcinoma | +272 months |
| UPN6 | 3 months | Pulmonary carcinoma | 3 months |
| UPN70 | 22 months | Pulmonary carcinoma | +22 months |
| UPN86 | 132 months | Pulmonary carcinoma | +146 months |
| UPN160 | 114 months | Pulmonary carcinoma | 112 months |
| UPN67 | 156 months | Cervical carcinoma | +181 months |
Six patients developed solid tumors (4 pulmonary cancers, 1 breast cancer and 1 cervical carcinoma) and 6 patients hematological malignancies (diffuse large B-cell lymphoma (DLBCL) in 4 cases, splenic marginal zone lymphoma (SMZL) in 2 cases) and 6 patients monoclonal gammopathies of undetermined significance (MGUS) (IgM)