Table 3.
Characteristics of the 10 patients analyzed by SNP arrays (UPN: Unique Patient Number)
| Patient | Karyotype | PCC (%) | FISH +i(3)(q10) (%) |
|---|---|---|---|
| UPN8b | 46–47,XX, +i(3)(q10) [3] /46,XX,del(2)(q22), −17, +mar [1] /45, X, −X [1] /46,XX [40] | Absent | Present (6 %) |
| UPN57a | 47,XY, +i(3)(q10) [5] /48,XY, +i(3)(q10), +12 [01]/46,XY,t(14;18)(q32;q22)[01]/47,XY,t(11;14)(q13;q32), +mar [01]/46,XY,add(3)(p26) [1] /47,XY, +22[01]/49,XY, +i(3)(q10), +8, +mar[01]/46,XY [39] | Absent | Present (7 %) |
| UPN136a | 46,XX [48]/PCC [2] | Present (4 %) | Present (4 %) |
| UPN71c | 47,XX, +X,del(6)(q15q26)[01]/46,XX,del(6)(q15q26),der(6)t(6;6)(q21;q23)[08]/46,XX,del(1)(q12),der(14)t(1;14)(p22;q32)[02]/46,XX[09] | Absent | Present (2 %) |
| UPN127b | 47,XY, +i(3)(q10) [3] /46,X,der(Y)t(Y;?)(q12;?) [3] /46,XY [12] | Absent | Present (12 %) |
| UPN138a | 46,XX,del(6)(q21q24) [6] /46,XX,der(8)t(3;8)(q11;q11),der(17)t(17;?)(p11;?) [2] /46,XX,del(17)(p11) [2] /46,XX,t(1;6)(q24;q21) [1] /46,XX,der(14)t(14;?)(p25;?) [1] /46,XX,dup(3)(p13p26) [1] /46,XX,der(4)t(4;?)(p16;?) [1] /46,XX [26] | Absent | Present (11 %) |
| UPN99a | 47,XX, +18 [2] /47,XX, +3 [1] /46,XX [37]/PCC [1] | Present (2 %) | Present (4 %) |
| UPN147a | 46,XX [50] | Absent | Absent |
| UPN73a | 46,XX [50] | Absent | Present (1.4 %) |
| UPN105a | 46,XY [46]/46,XY [cp 4] | Absent | Present (3 %) |
Depending on the quality of extracted DNA, we performed DNA arrays on aboth CD19+ and CD19− cells in 7 patients, bCD19+ cells in 2 patients and cCD19− cells in 1 patient. CCA and/or FISH detected +i(3)(q10) in 9/10 patients
PCC premature chromosome condensation