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. 2016 Mar 3;16:16. doi: 10.1186/s12935-016-0291-8

Table 3.

The top five enriched gene ontology (GO) terms functional enrichment of the differentially expressed genes

GO ID Term Gene counts P value
Up-regulated genes GO:0006955 Immune response 104 9.10E−18
GO:0001775 Cell activation 54 3.82E−13
GO:0002684 Positive regulation of immune system process 47 2.70E−12
GO:0050865 Regulation of cell activation 39 5.70E−12
GO:0045321 Leukocyte activation 46 1.86E−11
Down-regulated genes GO:0055114 Oxidation reduction 132 2.56E−16
GO:0006091 Generation of precursor metabolites and energy 80 2.93E−15
GO:0006811 Ion transport 141 4.19E−13
GO:0006818 Hydrogen transport 29 1.38E−12
GO:0015992 Proton transport 28 3.91E−12