Skip to main content
. 2016 Feb 3;113(8):E958–E967. doi: 10.1073/pnas.1519680113

Fig. 4.

Fig. 4.

Wild-type and mutant cation C complexes. (A) TXS harboring manually built cation C (H01equatorial, H11axial, and C03: magenta). (B) Superposition of TXS-V584M harboring manually built cation C (blue) with manually built cation C of TXS (gray). C13 hydrogens abstracted during R580-PPi–assisted deprotonation resulting in formation of V are shown (C13 hydrogens of TXS in red; C13 hydrogens of TXS-V584M in magenta). Distance between H13equatorial (H13e) of TXS-V584M and NH2 of R580 is 3.05 Å (magenta line); distance between H13e of TXS and NH2 of R580 is 3.87 Å (red line). Distance between H13axial (H13a) of TXS-V584M and O07 of PPi is 4.25 Å; distance between H13a of TXS and O07 of PPi is 4.83 Å.