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Viruses that cause minimal or no activation of RNase L as determined by monitoring rRNA integrity in A549 cells. Parental and RNase L-KO cells were infected at MOI = 20. Cells were lysed at 12 (LACV, VSV, SeV, EMCV), 21 (TMEV), or 60 (LCMV) hpi, and RNA integrity was analyzed on a Bioanalyzer. The positions of 18S and 28S rRNA are indicated.
