Fig. S8.

S1PR1 is required for the egress of endogenous effector CD4 T cells from the dLN after infection. (A) Experimental scheme: VSV-infected mice were administered orally with either vehicle or with 1 mg⋅kg⁻¹ FTY720 at day 4 p.i. (B) At day 6 p.i., dLNs were harvested and analyzed by FACS. LLO-tet⁺ VSV-specific CD4 T cell frequencies in the dLN 6 d p.i. after vehicle (Left) or FTY720 (Right) treatment. Dot plots represent CD4⁺ gated cells. Images are representatives of three different experiments with at least three mice per treated group.