Table S1.
Cellular proteins interacting with GFP-LANA-FL or GFP-LANA-NC (LANA Δ329–931) were identified by MS
| No. LANA-interacting proteins | proteins | LANA-FL | LANA-NC | ||||
| Times | Score | No. of peptide | Times | Score | No. of peptide | ||
| 1 | Lysine-specific demethylase 3A GN = KDM3A | 4 | 705.64 | 15 | 4 | 391.41 | 8 |
| 2 | Death domain-associated protein 6 GN = DAXX | 4 | 546.34 | 9 | |||
| 3 | Helicase-like transcription factor GN = HLTF | 4 | 329.48 | 7 | 4 | 557.17 | 12 |
| 4 | Sister chromatid cohesion protein PDS5 homolog A GN = PDS5A | 4 | 232.01 | 5 | 3 | 238 | 5 |
| 5 | FACT complex subunit SPT16 GN = SUPT16H | 4 | 122.89 | 3 | 4 | 408.91 | 9 |
| 6 | Core histone macro-H2A.1 GN = H2AFY | 4 | 94.27 | 2 | 4 | 182.28 | 3 |
| 7 | FACT complex subunit SSRP1 GN = SSRP1 | 4 | 89.26 | 2 | 4 | 166.94 | 3 |
| 8 | DNA repair protein complementing XP-C cells GN = XPC | 4 | 84.4 | 2 | 2 | 217.01 | 5 |
| 9 | Telomere-associated protein RIF1 GN = RIF1 | 3 | 412.85 | 7 | 4 | 979.53 | 19 |
| 10 | Mediator of DNA damage checkpoint protein 1 GN = MDC1 | 3 | 275.37 | 7 | 4 | 958.41 | 19 |
| 11 | Isoform 2 of Nuclear mitotic apparatus protein 1 GN = NUMA1 | 3 | 239.12 | 5 | 4 | 1,489.34 | 29 |
| 12 | Tyrosine-protein kinase BAZ1B GN = BAZ1B | 3 | 215.21 | 4 | 4 | 463.57 | 9 |
| 13 | SWI/SNF complex subunit SMARCC1 GN = SMARCC1 | 3 | 185.34 | 4 | 3 | 309.42 | 8 |
| 14 | AT-rich interactive domain-containing protein 1A GN = ARID1A | 3 | 133.87 | 3 | 3 | 309.49 | 8 |
| 15 | Centromere protein F GN = CENPF | 3 | 130.02 | 3 | 4 | 667.49 | 14 |
| 16 | DNA replication licensing factor MCM6 GN = MCM6 | 3 | 112.59 | 2 | 2 | 123.32 | 3 |
| 17 | DNA repair protein RAD50 GN = RAD50 | 3 | 108.28 | 3 | 4 | 163.56 | 4 |
| 18 | DNA topoisomerase 2-α GN = TOP2A | 3 | 93.39 | 2 | 4 | 460.74 | 10 |
| 19 | cGMP-AMP synthase GN = MB21D1 | 3 | 358.11 | 8 | 4 | 391.26 | 9 |
| 20 | Metastasis-associated protein MTA1 GN = MTA1 | 3 | 201.35 | 4 | 2 | 143.84 | 3 |
| 21 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 GN = SMARCE1 | 3 | 189.98 | 4 | 2 | 256.92 | 6 |
| 22 | Targeting protein for Xklp2 GN = TPX2 | 3 | 184.51 | 5 | 3 | 203.16 | 4 |
| 23 | PC4 and SFRS1-interacting protein GN = PSIP1 | 3 | 132.27 | 3 | 3 | 148.42 | 3 |
| 24 | Transcriptional repressor p66-alpha GN = GATAD2A | 3 | 130.53 | 3 | 1 | 89.37 | 2 |
| 25 | Putative oxidoreductase GLYR1 GN = GLYR1 | 3 | 120.92 | 2 | 3 | 119.51 | 2 |
| 26 | Torsin-1A-interacting protein 1 GN = TOR1AIP1 | 3 | 71.4 | 2 | 1 | 173.45 | 6 |
| 27 | Nucleosome-remodeling factor subunit BPTF GN = BPTF | 2 | 535.27 | 11 | 3 | 550.94 | 12 |
| 28 | Ras GTPase-activating protein-binding protein 2 GN = G3BP2 | 2 | 350.51 | 8 | 3 | 401.69 | 8 |
| 29 | DNA topoisomerase 2-beta OS = Homo sapiens GN = TOP2B | 2 | 370.91 | 8 | 3 | 242.56 | 5 |
| 30 | Remodeling and spacing factor 1 GN = RSF1 | 1 | 272.61 | 6 | 3 | 212.41 | 4 |
| 31 | Partitioning defective 3 homolog GN = PARD3 | 1 | 450.03 | 10 | 3 | 168.1 | 4 |
| 32 | Actin-like protein 6A GN = ACTL6A | 2 | 202.72 | 4 | 3 | 112.8 | 2 |
| 33 | Heterogeneous nuclear ribonucleoprotein D0 (Fragment) GN = HNRNPD | 3 | 111.93 | 2 | |||
| 34 | Centrosomal protein of 170 kDa GN = CEP170 | 2 | 168.23 | 3 | 3 | 104.13 | 2 |
| 35 | Src substrate cortactin OS = Homo sapiens GN = CTTN | 2 | 230.8 | 4 | 3 | 495.72 | 11 |
| 36 | 26S proteasome non-ATPase regulatory subunit 11 GN = PSMD11 | 1 | 102.16 | 2 | 3 | 111.26 | 2 |
| 37 | Ewing's tumor-associated antigen 1 GN = ETAA1 | 2 | 151.61 | 3 | 3 | 78.36 | 2 |
| 38 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 GN = SMARCAL1 | 2 | 290.1 | 7 | 3 | 201.21 | 5 |
List contains proteins with high frequency (≥3 times in four independently repeated LANA-FL or LANA-NC precipitations).