Fig. 2.

N1ICD OEx mice have no uterine glands. (A) Unlike control, OEx + KO, and KO mice, there are no glands in the uteri of N1ICD OEx mice at 3.5 dpc as detected by H&E staining. (B) The gland marker Foxa2 is expressed in the glandular epithelium of control, OEx + KO, and KO mice, whereas its expression is only present in the luminal epithelium of OEx mice. (C) Expression of Lif mRNA in GE cells of control mice and LE cells of N1ICD OEx mice at 3.5 dpc. (D) N1ICD OEx mice express comparable levels of Lif protein to control mice as measured by Western blot at 3.5 dpc. Ctrl, control. (Scale bar: 100 µm.)