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. Author manuscript; available in PMC: 2016 Mar 3.
Published in final edited form as: Cell Rep. 2015 Nov 25;13(10):2174–2188. doi: 10.1016/j.celrep.2015.10.071

Figure 1. Mipp1 encodes a highly conserved histidine phosphatase with active site residues dispersed throughout the coding region.

Figure 1

(A-B) Textshade alignment (A) and Unrooted Phylip Tree (B) of Mipps and Phytases from representative model organisms.

(C) Phyre2 predicted structure of Drosophila Mipp1.

(D) Phyre2 predicted configuration of active site residues in the active site pocket of Drosophila Mipp1. Acronyms: Dr = Danio Rerio; Mm = Mus musculus; Hs = Homo sapiens; Dd = Dictyostelium discoideum; Ag = Anopheles gambiae; Dm = Drosophila melanogaster; Cf = Cryptococcus neoformans; An = Aspergillis nigers