Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Nov 30;3(6):e00193. doi: 10.1002/prp2.193

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 Merck Inc. Pharmacology Research & Perspectives published by John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

PMC Copyright notice

Chemical structures and cellular activities of compound A. (A) Chemical structure of compound A. (B) Compound concentration‐dependent inhibition of TG synthesis in human intestinal epithelial HT‐29. Cells were preincubated with various concentrations of compound A for 30 min followed by [¹³C₁₈]‐oleic acid incubation. A representative labeled TG species, TG‐[¹³C₁₈]18:1‐[¹³C₁₈]18:1‐[¹³C₁₈]18:1, was used to represent TG levels in the presence of different concentrations of compound A. Results are expressed as mean ± SEM. IC50: 20 ± 0.3 nmol/L.