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. 2016 Feb 26;10:851–859. doi: 10.2147/DDDT.S97380

Figure 1.

Figure 1

The effects of PAP on the viability of BV2 cell.

Notes: BV2 cells were pretreated with PAP (0, 0.4, 2, 10, and 50 μg/mL) for 4 hours followed by LPS (100 ng/mL) stimulation for an additional 24 hours. Cell viability was measured by CCK-8 assay. Compared with the control group, pretreatment with 50 μg/mL of PAP significantly inhibited the cell viability (**P<0.05), while no significant difference was observed at the concentrations below 10 μg/mL (*P>0.05). The results are represented as the mean ± SD of three independent experiments.

Abbreviations: PAP, papaverine; LPS, lipopolysaccharide; CCK-8, Cell Counting Kit 8; SD, standard deviation; CON, control.