Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Jan 15;4(1):e00197. doi: 10.1002/prp2.197

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 The Authors. Pharmacology Research & Perspectives published by John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

3D overall structures of the Chimera 2 antibody. (A) Top view is the structures of the afucosylated Chimera 2 mAb. The crystallizable fragment (Fc) chain (afucosylated) is shown in blue white. The receptor is shown in magenta. The oligosaccharides are depicted as sticks representations. (B) Exploded view on the interaction interface between afucosylated crystallizable fragment (Fc) receptor and Fcγ RIIIa. Interatomic distances below the 4 Å are highlighted by black dashed lines by using the distance wizard implemented in PyMOL.