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. 2016 Feb 26;11:791–822. doi: 10.2147/IJN.S97476

Table S1.

Effects of PEG-AuNPs on the cell cycle of PANC-1 cells after 24 hours of exposure

Sample Concentration (M) G0/G1 phase
S phase
G2/M phase
Average SD Average SD Average SD
NT 0 51.88 0.96 12.27 0.08 31.09 1.46
AuPEG_1-treated cells 1.3×10−5 51.96 0.81 13.13 0.28 28.74 0.70
1.9×10−5 52.87 0.29 13.43 0.25 28.20 1.14
AuPEG_2-treated cells 1.4×10−6 55.92 0.64 12.13 0.34 27.29 1.15
2×10−6 54.13 1.74 12.82 0.57 27.98 1.80
AuPEG_3-treated cells 2.5×10−8 45.01 2.21 20.78 0.34 27.35 3.01
4×10−8 43.80 0.58 20.30 0.31 30.65 0.41
AuPEG_4-treated cells 2.5×10−8 39.99 2.96 19.61 0.34 32.21 1.61
4×10−8 41.04 0.11 19.66 0.28 33.73 0.80
Cells exposed to free 1.5×10−6 25.58 0.37 23.16 0.56 42.79 0.21
molecular DOX (PT)

Notes: Values for untreated (negative control [NT]) and 1.5 μM doxorubicin-treated (positive control [PT]) controls are also reported for comparison. Data are reported as average (nreplicates=2) ± standard deviation (SD).

Abbreviations: DOX, doxorubicin; PEG-AuNPs, polyethylene glycol-gold nanoparticles; AuPEG, PEG-coated AuNPs.