Table 1.
Average hydrodynamic diameter of PEG-AuNPs dispersed in PBS, FBS, or complete cell medium (ie, DMEM supplemented with 10% FBS) before and after incubation at 37°C for 24 hours as determined by NTA
| Sample | t=0 hour (nm) | t=24 hours (nm) |
|---|---|---|
| PBS | ||
| AuPEG_1 | 81±10.3 | 127±8.0 |
| AuPEG_2 | 129±4.9 | 97±1.4 |
| AuPEG_3 | 130±4.5 | 139±3.6 |
| AuPEG_4 | 133±3.4 | 97±0.8 |
| FBS | ||
| AuPEG_1 | 132±2.5 | 123±3.7 |
| AuPEG_2 | 120±2.5 | 116±7.8 |
| AuPEG_3 | 112±3.0 | 103±6.3 |
| AuPEG_4 | 113±3.7 | 99±10.6 |
| DMEM supplemented with 10% FBS | ||
| AuPEG_1 | 89±5.8 | 97±6.6 |
| AuPEG_2 | 96±3.4 | 94±3.9 |
| AuPEG_3 | 92±4.4 | 90±4.0 |
| AuPEG_4 | 107±7.0 | 99±5.7 |
Note: Data are reported as mode ± standard deviation.
Abbreviations: PEG-AuNPs, polyethylene glycol-gold nanoparticles; PBS, phosphate-buffered solution; FBS, fetal bovine serum; DMEM, Dulbecco’s Modified Eagle’s Medium; NTA, nanoparticle tracking analysis; AuPEG, PEG-coated AuNPs.