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. 2016 Mar 3;11(3):e0150526. doi: 10.1371/journal.pone.0150526

Table 1. Interaction of Psi and PsiC with hemin.

Drug (μM)	Molar ratio Hemin:Drug	Absorbance ratio A₄₃₀/A₄₀₀
		(A)	(B)
Control	1:0	0.23	0.23
Artemisinin
39.75	1:5	0.25	0.27^*
79.50	1:10	0.28^*	0.35^*
119.25	1:15	0.32^*	0.41^*
PsiC
7,65	1:1	0.27^*	0.25
15.30	1:2	0.35^*	0.27^*
22.95	1:3	0.41^*	0.30^*
30.60	1:4	0.45^*	0.34^*
38.25	1:5	0.48^*	0.35^*
Psi
7.65	1:1	0.26^*	0.25
15.30	1:2	0.26^*	0.27^*
22.95	1:3	0.27^*	0.28^*
30.60	1:4	0.27^*	0.30^*
38.25	1:5	0.29^*	0.32^*
45.90	1:6	0.32^*	0.37^*

Hemin interaction was assayed spectrophotometrically under non-reducing (A) and reducing conditions (B), by monitoring the Soret band absorption.

*Significant differences (p<0.05) when compared to the control, as assessed by Student's t-test.