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Cathepsin A and NEU1 activities were measured in the tissue homogenates of scAAV2/8LP1-PPCA-treated Neu1−/−;NEU1V54M mice (n=4) and untreated mice (n=4); a) Cathepsin A and, b) NEU1 activities were higher in tissues from rAAV-treated Neu1−/−;NEU1V54M mice than in the corresponding untreated mice; data are represented as mean ± s.d. (error bars). Adapted from Bonten et al. Biochim, Biophys Acta 2013, with permission of Elsevier.
