Table 5.
Pharmacokinetic properties of 9
| ID | route | Dose (mg/kg) | Tmax (h)a | Cmax (ng/mL)b | AUClast (h*ng/mL)c | T1/2 (h)d | CL (mL/min/kg)e | Vss (L/kg)f | F (%)g |
|---|---|---|---|---|---|---|---|---|---|
| 9 | IV | 2 | – | 158.56 | 241.30 | 1.40 | 135.88 | 18.38 | – |
| PO | 10 | 0.5 | 204.25 | 795.29 | – | – | – | 66 |
Time for peak plasma concentrations.
Peak plasma concentrations.
Area under the concentration time curve.
Terminal half-life.
Plasma Clearance.
Volume in steady state.
Bioavailability.