Fig 5. A shift in the balance omega 6 and omega 3 fatty acids and increased pro-inflammatory eicosanoid production in the MCT-treated rat lung.

The ratio between pre-PH and control metabolites show both significant increases (red boxes) for omega 6, omega 3 fatty acids and eicosanoids and a trending decrease (light green box) for stearidonate (A). The pro-inflammatory prostaglandins E2, D2, J2 and leukotriene B5 are also significantly increased in the pre-PH lung (N = 10, p<0.05, B).