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. Author manuscript; available in PMC: 2017 Mar 2.
Published in final edited form as: Neuron. 2016 Feb 18;89(5):1059–1073. doi: 10.1016/j.neuron.2016.01.023

Figure 4. Postsynaptic CB1Rs modulate Ih in SPCs.

Figure 4

A) Experimental paradigm. mEC: medial entorhinal cortex; Red triangle: cells expressing the viral vector, lacking CB1R (CB1R− cells); Black: uninfected, CB1R+ cells.

B) Peak sag amplitudes recorded at −100 pA in CB1R− and CB1R+ SPCs (left) and DPCs (right) before and after WIN application (n: CB1R− SPCs: 10; CB1R− SPCs + WIN: 15; CB1R+ SPCs: 13; CB1R+ SPCs+WIN: 15; CB1R− DPCs: 11; CB1R− DPCs+WIN: 13; CB1R+ DPCs: 14; CB1R+ DPCs+WIN: 13). The effect on sag amplitude was similar for all current injections between −400 and −100 pA (Tables S1 and S2).