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(Top panel) Mesenteric lymph node T cells were cultured in the presence of control Ig, anti-CD3 antibody, or a cocktail for stimulation of Th17 cells. T cell stimulation by either pan-T cell activation or Th-17 cell activation resulted in decreased Rc3h1 gene expression, suggesting that during the normal process of T cell immune activation, Rc3h1 expression is suppressed. (Bottom panel) Confirmation that Th17 stimulation specifically induces Th17 gene expression.
