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. 2016 Jan 4;291(10):4998–5008. doi: 10.1074/jbc.M115.675306

FIGURE 5.

FIGURE 5.

Interactions of eL4 with TM10′ in transporters with a LeuT-fold. A, detail of the PutP model shown in Fig. 1 highlighting eL4 with Glu-311 and TM10′ with Ala-404. B, detail of the crystal structure of vSGLT (Protein Data Bank 3DH4 (17)) highlighting the interaction between Asp-336 in eL4 and Ala-423 in TM10′. C, detail of the crystal structure of LeuT in an inward-open conformation (Protein Data Bank 3TT3 (13)) highlighting the interaction between Ala-319 in eL4 and Asp-401 in TM10. Distances highlighted by dotted lines are in Å.