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. 2016 Jan 7;291(10):5278–5298. doi: 10.1074/jbc.M115.678177

FIGURE 18.

FIGURE 18.

Schematic of cell spreading on amyloid fibrils. Proposed cell adhesion on amyloid fibrils mediated by lipid-fibril interactions. This is followed by integrin clustering and activation of downstream signaling cascades that lead to the formation of focal adhesions and cell spreading.