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. 2016 Feb 18;4(1):e3. doi: 10.2196/medinform.4842

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©Illapha Cuba Gyllensten, Alberto G Bonomi, Kevin M Goode, Harald Reiter, Joerg Habetha, Oliver Amft, John GF Cleland. Originally published in JMIR Medical Informatics (http://medinform.jmir.org), 18.02.2016.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Medical Informatics, is properly cited. The complete bibliographic information, a link to the original publication on http://medinform.jmir.org/, as well as this copyright and license information must be included.

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Generated example data with the underlying trend in NITTI are shown in the top graph. The resulting output of the three algorithms, normalized to the last measure to show the qualitative difference between the algorithms, is shown in the bottom graph.