Table 1.
Characteristic at Baseline | 100% Able to Work (N = 4382) |
10%–90% Able to Work (N = 471) |
0% Able to Work (N = 947) |
P Value | |||
---|---|---|---|---|---|---|---|
n | % | n | % | n | % | ||
Median age, IQR | 37 | 31–43 | 38 | 33–45 | 39 | 34–45 | <.001 |
Male gender | 3201 | 73.1 | 293 | 62.2 | 618 | 65.3 | <.001 |
Transmission | |||||||
MSM | 2129 | 48.6 | 111 | 23.6 | 181 | 19.1 | <.001a |
Heterosexual | 1812 | 41.4 | 201 | 42.7 | 372 | 39.3 | |
PWID | 267 | 6.1 | 138 | 29.3 | 346 | 36.5 | |
Other | 174 | 4.0 | 21 | 4.5 | 48 | 5.1 | |
White ethnicity | 3210 | 73.3 | 379 | 80.5 | 773 | 81.6 | <.001 |
Low educational attainment | 994 | 22.9 | 163 | 35.9 | 325 | 36.1 | <.001 |
Hepatitis C coinfection | 786 | 17.9 | 191 | 40.6 | 452 | 47.3 | <.001 |
Hepatitis B coinfection (antigen HBs positive) | 224 | 5.1 | 20 | 4.3 | 62 | 6.6 | .117 |
Prior AIDS-defining condition | 532 | 12.1 | 120 | 25.5 | 354 | 37.8 | <.001 |
Active injecting drug use | 78 | 1.8 | 60 | 12.7 | 154 | 16.3 | <.001 |
Opiate substitution program | 280 | 6.4 | 83 | 17.6 | 249 | 26.3 | <.001 |
Psychiatric disorder | 229 | 5.2 | 66 | 14.0 | 186 | 19.6 | <.001 |
Median HIV-RNA, IQR | 4.7 | 4.1–5.2 | 4.8 | 3.9–5.3 | 4.9 | 4.2–5.5 | <.001 |
Median CD4 cell count, IQR | 263 | 160–372 | 196 | 65–325 | 157 | 54–291 | <.001 |
CD4 cell count | |||||||
<50 | 386 | 8.9 | 101 | 21.4 | 233 | 24.6 | <.001a |
50–99 | 276 | 6.3 | 42 | 8.9 | 108 | 11.4 | |
100–199 | 828 | 18.8 | 94 | 20.0 | 213 | 22.5 | |
200–349 | 1621 | 37.0 | 135 | 28.7 | 225 | 23.7 | |
>350 | 1271 | 29.0 | 99 | 21.0 | 168 | 17.8 | |
cART | |||||||
PI | 2354 | 53.7 | 273 | 58.0 | 598 | 63.1 | <.001a |
NNRTI | 1735 | 39.6 | 155 | 32.9 | 284 | 30.0 | |
Other | 293 | 6.7 | 43 | 9.1 | 65 | 6.9 | |
Time period | |||||||
1998–2000 | 855 | 19.5 | 144 | 30.6 | 330 | 34.9 | <.001a |
2001–2005 | 1133 | 25.9 | 164 | 34.8 | 292 | 30.8 | |
2006–2012 | 2394 | 54.6 | 163 | 34.6 | 325 | 34.3 |
Abbreviations: AIDS, acquired immune deficiency syndrome; cART, combination antiretroviral therapy; HB, hepatitis B; HIV, human immunodeficiency virus; IQR, interquartile range; MSM, men who have sex with men; NNRTI, nonnucleoside reverse-transcriptase inhibitors; PI, boosted protease inhibitors; PWID, people who inject drugs; RNA, ribonucleic acid.
a χ2 test.