Skip to main content
. 2016 Feb 15;196(6):2779–2787. doi: 10.4049/jimmunol.1500295

FIGURE 3.

FIGURE 3.

Effect of FK565 on the production of CCL2, IL-6, TNF, and NO in sera from pregnant mice, placentae, and fetuses. (A–C) Cytokine, chemokine, and NO levels were determined in the samples [(A), serum of the mother; (B), placental homogenates; (C), fetal homogenates] after 6 and 48 h from pregnant mice treated with indicated doses of FK565 at E14.5. The mean values and standard deviations are shown (n = 4–5 for each group). (D) Histologic evaluation of pregnant mice, placentae, and live fetuses. The perivascular regions are indicated with arrows. *p < 0.05; **p < 0.01 relative to the PBS (0 μg of FK565) 6-h control (Dunnett test).