Table 2.
TTFD (months) of donepezil in a 3-year follow up of new users (n = 1,999)
| Period, months | Probability of discontinuation, % | Probability of continuing treatment | Cumulative discontinuations, n | Patients discontinued, n | Proportion of donepezil dispensings |
|---|---|---|---|---|---|
| Single dispensings | – | – | 124 | – | |
| 6 months | 35 | 0.65 | 699 | 699 | 81.0 |
| 12 months | 49 | 0.51 | 980 | 281 | 69.3 |
| 18 months | 59 | 0.41 | 1,178 | 198 | 55.4 |
| 24 months | 77 | 0.33 | 1,328 | 150 | 45.9 |
| 36 months | 93 | 0.17 | 1,674 | 222 | 32.5 |
| ≥36 months (censored) | >94 | ≥0.16 | 325 | ≥27.5 | |
| Total after study period | 1,999 | 1,674 | |||