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. 2015 Dec 18;5(3):503–516. doi: 10.1159/000440859

Table 1.

DAPHNE scale

Normal (0) Very mild (1) Mild (2) Moderate (3) Severe (4)
Disinhibition
Loss of social convenience no trouble subject makes unpleasant, hurtful comments to family members; subject seeks out contact with strangers subject makes unpleasant, hurtful comments to strangers subject is unable to participate in any social activity because of inappropriate social behavior (impatience, etc.) subject interrupts strangers’ activities, behaves inappropriately and disturbs public order (obscene words, urination, etc.)
Inappropriate joviality no trouble subject is jovial and laughs unreasonably but in appropriate situations and can stop when asked to subject is jovial and laughs unreasonably in appropriate situations but cannot stop when asked to subject is jovial in embarrassing situations (talks to strangers, etc.) subject is jovial and says unacceptable words (jokes, sneers) in inappropriate situations (at funerals, with young children, etc.)
Unrestrained spending habits no trouble subject buys a lot by mail order or repeatedly buys the same low-value things, but can listen to reason subject buys a lot by mail order or repeatedly buys the same low-value things, but cannot listen to reason subject buys lots of useless things, buys expensive objects and does not understand that they are excessive and inappropriate subject is indebted because of lots of expensive purchases or gambling (card games, casino, etc.)
Sexual disinhibition no trouble subject makes inappropriate sexual comments or jokes, but can stop if asked to subject makes inappropriate and uncontrolled sexual comments or jokes, which he/she then acts on subject makes inappropriate and uncontrolled sexual comments or jokes, which he/she then acts on; subject is indecent (undresses in inappropriate places, etc.) subject displays unwanted and inappropriate sexual behavior (public masturbation, sexual touching of a minor, sexual attraction to animals, etc.)

Apathy
Loss of initiative, social interest no trouble subject can take part in usual activities, but must be encouraged to do anything outside of the ordinary subject can take part in usual activities, but does not complete them; subject can restart an activity, but only with stimulation subject interrupts activities and does not restart them, even with stimulation; subject does not want to do usual activities subject has no interest; does not do anything despite stimulation, stays in his/her seat or in bed all day

Loss of empathy
Emotional blunting, indifference no trouble subject complains about loss of emotion towards relatives subject shows little interest in stories from relatives or in emotionally current matters; subject has difficulty expressing feelings subject is indifferent to relatives, does not care about them, and is not concerned when people speak about him/her subject is unable to express or decipher any emotion, can have inappropriate emotional responses

Perseverations
Fixed ideas, stereotypical behavior no trouble subject collects usual objects or has trouble getting rid of things or has routine activities subject collects unusual objects or does not throw anything away, has ritualized activities or has obsessions (hours, etc.), but this is consistent with social life subject collects lots of objects or has difficulty sitting still, has obsessional rituals that interfere with social life subject has continuous rituals (grinding of teeth, rubbing of body, grasping of objects, repetition of words or sentences); subject does not stand still

Hyperorality
Eating disorders, new preference for sweets no trouble subject has a new preference for sweets subject has new or bizarre food preferences but can listen to reason subject eats or drinks excessively and cannot listen to reason (padlock on cupboard, etc.) subject eats and drinks everything within reach, including in other people's plates or glasses, or eats inedible substances
Bulimia, gluttony no trouble subject eats much more, has put on weight subject eats gluttonously, voraciously, without getting dirty subject eats quickly and gets dirty, takes big pieces, risking choking subject eats with hands, uncleanly, does not cut his food, keeps food in mouth; subject has put on a lot of weight

Neglect
Personal neglect no trouble subject looks less neat subject must be stimulated to wash or change clothes subject can wash or change clothes only when threatened or tricked subject has very poor hygiene (dirty fingernails, dirty hair, dirty clothes, etc.)

DAPHNE-6 (screening) is computed from the six synthetic binary domains. For a given domain, score 1 point if at least one symptom is present, regardless of the number of items present in the domain and irrespective of the severity. The maximum score is six.

DAPHNE-40 (diagnosis) is computed as the sum of the boxes of the ten items. The maximum score is 40.