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. 2016 Mar 7;22(9):2749–2759. doi: 10.3748/wjg.v22.i9.2749

Table 1.

Studies with different basal immunosuppression schedules for patients with hepatocellular carcinoma after liver transplantationv

Ref. Year Immunosuppressor type Evaluated parameters Recurrence rate P value
Rodríguez-Perálvarez et al[10] 2013 CNI Low exposure 1st vs high exposure 1st 27.7% vs 14.7% at 5 yr 0.007
Vivarelli et al[16] 2005 CSA Low exposure vs high exposure 0% vs 33.3% < 0.001
Vivarelli et al[14] 2008 TAC Low exposure vs high exposure 9.1% vs 50% 0.001
Menon et al[21] 2013 SRL and CNIs SRL vs CNIs 4.9%-12.9% vs 17.3%-38.7% NA
Cholongitas et al[22] 2014 CNIs and mTORi CNIs vs mTORi 22% vs 44% < 0.050

CNI: Calcineurin inhibitors; CsA: Cyclosporine A; TAC: Tacrolimus; SRL: Sirolimus; mTORi: The mammalian target of rapamycin inhibitors; NA: Not analyzed.