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. 2016 Mar 4;6:22685. doi: 10.1038/srep22685

Figure 7. The K280R mutation mitigated hTau-induced climbing defects in old flies.

Figure 7

Climbing ability was monitored over time in flies over-expressing either hTau-wt (red), hTau-K280Q (grey) or hTau-K280R (blue) in the adult nervous system (elavGS-driven). Day 13: *p < 0.05, RU486-induced hTau-K280R vs. RU486-induced hTau-K280Q and ****p < 0.0001, RU486-induced hTau-K280R vs. RU486-induced hTau-wt; two-way ANOVA followed by Tukey’s post hoc test.