Figure 3. Intracellular Ca²⁺ handling properties in cardiomyocytes from young or old WT and MIF^−/− mice.

(A) Resting Fura-2 fluorescence intensity (FFI); (B) Electrically-stimulated in FFI (ΔFFI); (C) Intracellular Ca²⁺ decay rate (single exponential); (D) Intracellular Ca²⁺ decay rate (bi exponential). Mean ± SEM, n = 89–119 cells per group, *p < 0.05 vs. WT young group, ^#p < 0.05 vs. WT old group.