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. 2016 Jan 19;184(1):90–100. doi: 10.1111/cei.12747

Figure 5.

Figure 5

Effect of dengue NS1 on annexin V expression by T cells. (a) Dengue NS1 antigen levels (PanBio units) and annexin V expression was assessed in 22 patients with acute dengue. NS1 antigen levels (PanBio units) correlated positively with the proportion of annexin V‐expressing T cells (Spearman's r = 0·63, P = 0·001). (b) Annexin V expression by CD4+ and CD8+ T cells following co‐culturing of peripheral blood mononuclear cells (PBMCs) with dengue NS1. Annexin V expression on CD4+ and CD8+ T cells of 10 healthy individuals was determined by flow cytometry following co‐culture with media alone or dengue NS1 concentrations of 250 ng/ml and 500 ng/ml for 24 h.