Table 3.

Weighted ORs and 95% CIs of the association between BMI Change and Breast Cancer Risk

	BMI measurement closest to breast cancer diagnosis (n=172)		Analysis based on 102 breast cancer cases whose BMI measurement was prior to their diagnosis
	Model a	Model b	Model a	Model b
BMI Change
Normal throughout	Reference	Reference	Reference	Reference
Normal to Overweight	1.3 (0.80-2.02)	1.5 (0.90-2.45)	1.1 (0.59-2.17)	1.5 (0.75-2.92)
Normal/Overweight to Obese	2.0 (1.15-3.56)*	2.1 (1.11-3.79)*	3.1 (1.58-5.93)*	3.4 (1.66-6.99)*
Overweight/Obese throughout	1.0 (0.42-2.38)	1.3 (0.54-3.36)	1.1 (0.44-2.55)	1.5 (0.53-4.01)

^*Statistically significant at p<.05. Model a was adjusted for variables that were significantly different for cases and controls: age (continuous), race/ethnicity (non-Hispanic White, non-Hispanic Black, Hispanic and Other race), education (less than high school education, high school graduate and college education). Model b was adjusted for all variables that are confirmed or suspected risk factors for breast cancer: age (continuous), race/ethnicity (non-Hispanic White, non-Hispanic Black, Hispanic and Other race), education (less than high school education, high school graduate and college education), marital status (married or living with partner Yes/No), age at menarche (continuous), age at menopause (continuous), smoking (smoked at least 100 cigarettes in life Yes/No) and total cholesterol (mg/dl).