Table 3.
Analysis of the modified remodeling index (mRI), vessel dimensions, AHA-lesion-type distribution, and plaque-components in symptomatic and asymptomatic arteries
| Vessel dimensions (mean) | Symptomatic ICA (n = 102) | Asymptomatic ICA (n = 100) | p-value |
|---|---|---|---|
| Modified remodeling index | 2.22 ± 0.80 | 2.21 ± 0.85 | n.s. |
| Lumen area [mm2] | 19.8 ± 9.4 | 22.1 ± 9.2 | n.s. |
| Wall area [mm2] | 29.9 ± 13.4 | 27.7 ± 9.7 | n.s. |
| Outher wall area [mm2] | 49.7 ± 18.0 | 49.8 ± 15.9 | n.s. |
| Normalized wall index | 0.60 ± 0.11 | 0.56 ± 0.09 | 0.0056 |
| Wall thickness [mm] | 1.8 ± 0.6 | 1.6 ± 0.4 | 0.0221 |
| AHA lesion type distribution | |||
| AHA LT I (%; x/n) | 23.5 % (24/102) | 25.0 % (25/100) | n.s. |
| AHA LT III (%; x/n) | 19.6 % (20/102) | 27.9 % (27/100) | n.s. |
| AHA LT IV/V (%; x/n) | 20.6 % (21/102) | 18.0 % (18/100) | n.s. |
| AHA LT VI (%; x/n) | 19.6 % (20/102) | 4.0 % (4/100) | 0.0008 |
| AHA LT VII (%; x/n) | 16.7 % (17/102) | 26.0 % (26/100) | n.s. |
| Plaque components | |||
| Intraplaque hemorrhage (%; x/n) | 18.6 % (19/102) | 4.0 % (4/100) | 0.0014 |
| Lipidrich necrotic core (%; x/n) | 39.2 % (40/102) | 22.0 % (22/100) | 0.0095 |
| Calcification (%; x/n) | 30.4 % (31/102) | 34.0 % (34/100) | n.s. |
| Ulceration (%; x/n) | 5.9 % (6/102) | 1.0 % (1/100) | n.s. |
| Thrombus (%; x/n) | 2.0 % (2/102) | 0.0 % (0/100) | n.s. |