Table 2.
Normal tissue dose-volume constraints and standardised contouring nomenclature
| Organ | Standardised name | Parameter | Investigational treatment | |
|---|---|---|---|---|
| Constraint | 28Gy in 1# | 48Gy in 4#/2wks | ||
| Normal Lungs | V5 < 1000 cc | 66 % 7.4Gy | 66 % 12.4Gy, (max 3.1Gy per fraction) | |
| Heart | Heart | Maximum dose (0.03 cc) < 15 cc | 22Gy | 34 Gy, (max 8.5 Gy per fraction) |
| 16Gy | 28 Gy, (max 7 Gy per fraction) | |||
| Oesophagus | Oesophagus | Maximum dose (0.03 cc) | 15.4Gy | 30Gy, (max 7.5Gy per fraction) |
| Spinal Cord | SpinalCord | Maximum dose (0.03 cc) | 12Gy | 20.8Gy, (max 5.2Gy per fraction) |
| Brachial plexus | BrachialPlexus | Maximum dose (0.03 cc) | 15Gy | 24Gy, (max 6Gy per fraction) |
| Skin (5 mm subcutis) | Skin | Maximum dose (0.03 cc) < 10 cc | 26Gy | 36 Gy, (max 9 Gy per fraction) |
| 23Gy | 33.2 Gy, (max 8.3 Gy per fraction) | |||
| Chest walla | ChestWall | <70 cc | b26Gy to full thickness | 30Gy |
| Great Vessels | GreatVessel | Maximum Dose (0.03 cc) | 30 Gy | 49 Gy, (max 12.25 Gy per fraction |
| Liver | Liver | V20, V30 | No constraint, but dose/volume parameters to be documented | No constraint, but dose/volume parameters to be documented |
aChest wall dose limit may be exceeded if rib structure lies close to or in contact with the PTV
b26Gy isodose line should not cross full thickness of the chest wall structure
Definitions: Vx describes the volume that receives xGy, e.g. V5 < 66 % represents that the volume of specified OAR receiving 5 Gy shall be less than 66 %