Figure 3. The activity of WT hPXR and hPXR mutants in LS174T cells.
LS174T cells transiently transfected with empty vector (EV), WT hPXR (hPXR), or hPXR mutant as indicated, CYP3A4-luc, and CMV-Renilla were treated with DMSO or different concentrations of agonists as indicated for 24 h prior to luciferase assay.